DNA Lounge has been one of San Francisco's most popular nightclubs for over thirty years, hosting an always-eclectic variety of events, including all-ages live music, 18+ dance parties, burlesque shows, lecture series and private parties. With two stages, four dance floors, seven bars and a full-service late-night restaurant and cafe, DNA Lounge has won over 60 "best of" awards from local publications and has been voted "Best Dance Club" every year since 2008. While the large venue is considered pretty cool with fun times watching bands and hanging out with friends, the upstairs room has been noted for having terrible sound with microphones that kept cutting out during sets, making it hard to enjoy the bands. The pizza has also been described as barely edible and overpriced, with the vegetarian options tasting like undercooked cardboard. Despite these drawbacks, DNA Lounge remains a popular destination, particularly for live music, with visitors driving down from Reno just to see the concerts. The venue is also praised for its great service and nostalgic atmosphere, with one reviewer reminiscing about seeing Fishbone perform there in the 1990s. Overall, DNA Lounge is considered an iconic event venue in the SOMA area of San Francisco, offering one of the best options for late-night pizza in the neighborhood.
I attended Flag Alley, a special event on a weeknight. The staff was so wonderful. Friendly service, great vibe. They have a pizza kitchen. Though I didn't get any food the smells were deliciously tempting. I was very happy with the sound system and light show and danced my ass off. Thank you DNA for a fabulous night!
July 2026
Attended a New Money MMA event. They showcased good fights. Cool venue. Good pizza.
July 2026
Heaven is real and it has a $5 cover. Monday night's Death Guild is a place of true joy and beauty.
