Sellers Bros #21 is a grocery store known for its variety of Mexican meat and beer, making it a popular choice for those seeking authentic ingredients. Customers appreciate the good prices on meal prep bowls and large cans of beans, often finding better deals than online retailers. The store has a clean layout and is handicap accessible, with electric shopping carts available and ample parking. Shoppers enjoy the absence of self-checkout lanes, valuing the friendly service from cashiers. However, some customers have noted that certain fruits and vegetables may not be fresh and have suggested the need for more bilingual staff to assist non-Spanish speakers. Overall, Sellers Bros #21 offers a convenient shopping experience with a unique selection, though prices can be higher than expected.